Neurosurgery Clinics of North America
Volume 22, Issue 3 , Pages 359-366, July 2011

Stereotactic Biopsy Considerations for Pineal Tumors

  • Brad E. Zacharia, MD

      Affiliations

    • Department of Neurological Surgery, Columbia University, 710 West 168th Street, 4th Floor, New York, NY 10032, USA
    • Corresponding Author InformationCorresponding author.
  • ,
  • Jeffrey N. Bruce, MD

      Affiliations

    • Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, Room 434, Neurological Institute, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA

Pineal region tumors represent 0.4% to 1.0% of intracranial tumors in American literature. Obtaining a tissue diagnosis is the cornerstone of the rational management of pineal lesions. The initial surgical decision involves choosing between a stereotactic biopsy and open microsurgical procedures. Open resection facilitates the maximal removal of tumor volume and has diagnostic accuracy and improved prognosis. Stereotactic biopsy is less invasive and has a lower risk of complications. A review of all major series reporting stereotactic biopsy for pineal region lesions reveals a mean diagnostic yield of 94%, with a morbidity of 1.3% and a mortality of 8.1%.

Keywords: Pineal tumors, Biopsy, Stereotactic, Pineal region

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 The authors have nothing to disclose.

PII: S1042-3680(11)00053-2

doi:10.1016/j.nec.2011.05.008

Neurosurgery Clinics of North America
Volume 22, Issue 3 , Pages 359-366, July 2011